The use of topical oral oxygen therapy (TOOT) has gained attention for its antibacterial and regenerative properties, as well as its ability to accelerate wound healing This report presents the case with postoperative palatal necrosis successfully treated with a TOOT formulation oxygen active gel (blue®m). A 33-year-old male patient presented with the primary complaint of needing rehabilitation of the anterior maxillary region. Clinical and imaging examinations revealed a deficient maxillary ridge and an enlarged incisive foramen. The treatment plan involved nasopalatine deflation with guided bone regeneration using particulate synthetic bone graft and a collagen membrane. Seven days post-surgery, the patient returned with minimal pain but displayed necrotic tissue on the palate. The necrotic tissue and a portion of the contaminated biomaterial were removed, and the area was thoroughly cleansed with a saline solution. A thick layer of active oxygen gel (blue®m) was then applied to the palatal lesion. The patient was instructed to apply the gel three times daily for 30 days and attended follow-up appointments every two days. After 12 days, rapid healing and significant clinical improvement were observed, with the patient reporting no pain or sensitivity. By day 34, the lesion had fully closed, and re-epithelialization was achieved. Within limitations, this case report showed a complete resolution of palatal necrosis after nervus deflation using TOOT with active oxygen gel (blue®m), this therapy seems to accelerate the healing process in this case.

Tatiana Deliberador completed her Post-Doctorate in Periodontics in 2016. She has been working as a professor in postgraduate programs in the areas of Periodontics and Implantology since 2006. She has published over 150 scientific articles. She is currently a professor at ILAPEO College and editor-in-chief of the Journal of OroFacial Innovation and Science (JOIS), in Curitiba/PR, Brazil.