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Elvira Akhmedova

Polyclinika.ru, Russian Federation

Title: Challenging diagnosis of amebiasis in a non-endemic region: case report

Abstract

Introduction. In   Russia,   amebiasis is sporadically registered mainly in the southern regions.  An endemic area is the Republic of Dagestan. 

Aims. This clinical case illustrates  challenges  in  the  diagnosis  of  amebial  colitis  related  to  low  awareness  of  physicians  of  parasitic  diseases  in  non-endemic  regions.  

Result. A 38-year-old female patient  living in  Moscow was  initially  misdiagnosed  with  Crohn's  disease.   Erosive   and   ulcerative   colonic   lesions   found  at  colonoscopy  were  interpreted  by  a  gastroenterologist  as  symptoms  of  an  inflammatory  bowel disease. No differential diagnosis with infections and parasitic diseases was performed.  Long  (2  years)  persistence of symptoms  despite  treatment  with  5-aminosalicylic  agents  for  suspected  Crohn's disease, absence of any significant laboratory  abnormalities  and  no  history  of  travelling  to  Asian  countries  were  the  reason  for  subsequent  additional  diagnostic  work-up.  After  the  patient  was  finally  diagnosed  with  intestinal  amebiasis,  she  was  treated  with  metronidazole  with  some  positive  effect  of  decreased  abdominal  bloating  and  bowel  growling.  At  the  control  colonoscopy,  there  was  a  positive  trend  seen  in  colonic  mucosa, with healing of ulcers without any scarring. No protozoan cysts were any more found in her feces. According to the recommendations, a specialist in infectious diseases and a gastroenterologist regularly sees the patient.  

Conclusion. Expansion  of  amebiasis  outside  endemic  regions  points  to  the  necessity  to perform a wider diagnostic work-up in cases of mucosal lesions found at colonoscopy. Not every lesion is inflammatory bowel disease and patients should be widely exclude the infection. 

Biography

Elvira Akhmedova works at Polyclinika.ru in Russian Federation.